The Liberty Daily 
(The Daily Caller)—Food and Drug Administration (FDA) Commissioner Marty Makary is reportedly resigning from his role on Tuesday.
Makary is stepping down from his role on Tuesday after just 13 months leading the agency, Politico reported, citing an anonymous administration official. His reported exit comes after The Wall Street Journal (WSJ) first reported on Friday that the president had signed off on a plan to oust Makary from the agency, citing anonymous sources familiar with the matter.
The White House did not immediately respond to the Daily Caller News Foundation’s request for comment.
There has been recent speculation that Makary might exit his position at the FDA amid concerns over contentious decisions involving drug approvals, vaccines and the agency’s handling of the abortion pill Mifepristone, U.S. News and World Report reported on Friday.
Makary, a surgical oncologist and health policy researcher, was confirmed as FDA commissioner by a bipartisan vote of the U.S. Senate in March 2025 and was sworn in the following month. Trump had previously criticized Makary for not acting fast enough to approve flavored vaping and nicotine products, the WSJ reported on May 5 citing sources familiar with the matter.
The FDA announced on Tuesday that it was authorizing certain fruit-flavored vapes for adults 21 and over for the first time. Bret Koplow, acting director of the FDA’s Center for Tobacco Products, said in a Tuesday statement that “by helping to prevent youth use, device access restrictions are a potential game changer.”
Some Trump administration officials, including Health and Human Services Secretary Robert F. Kennedy Jr., had previously considered reducing Makary’s responsibilities at the FDA amid complaints about his management style, the WSJ reported in November 2025 citing people with knowledge of the matter.
“He [Makary] will not be missed by a single career person,” an anonymous FDA staffer told Politico on Friday in response to reports of his pending exit. “And we will only regret it when they manage to find someone worse.”
